What are exosomes?
Exosomes are extracellular vesicles that are produced by mesenchymal stem cells which are involved in cell communication. Other cells react to the messaging signals from the exosomes and will change their behavior accordingly. Scientists are now able to isolate and deliver these beneficial signalers directly rather than the stem cells themselves.
Exosomes are isolated from donated human amniotic mesenchymal stem cells and purified using proprietary processing. The unique benefit of these exosomes is that they are stem cell-derived and bring a wide array of growth factors. Because they’re so small and nimble, exosomes can remain hidden in the bloodstream, and carry multiple doses of proteins across barriers that cells are not able to cross.
What is exosome therapy for hair loss?
By injecting exosomes and growth factors, it has been clinically shown to help regenerate and regrow hair as a treatment for hair loss in both men and women in the earlier stages of hair loss.
Exosomes are stem cells per say. Instead, they are the building blocks of such. They generate within their cells of origin if the multivesicular body fuses with the cell membrane, thereby releasing intraluminal vesicles as exosomes. These small cellular products contain both RNA and, even of greater import, mRNA; the initiator of protein manufacturing.
These protein building blocks' roles are dependent on their cell of origin. Many act as signalers for bodily functions, such as coagulation, as well as cellular growth to facilitate said bodily functions. Such signaling and growth factors, studies currently show, are a result of the exosome's origin. Near all, however, have a number of useful growth factors/signalers:
MIP-1: A recruiter of mononuclear cells
VEGF: A stimulator to encourage blood vessel formation
SCF: An encourager of stem cell and melanocyte growth
FGF: A growth factor that signals cells to encourage biological development
TGFß3: A gene variant that, among other things, converts inflammatory T Cells into anti-inflammatory T-Cells
Research into exosomes is happening for a number of purposes; male and female sexual functioning/revitalization, joint regeneration, and facials. Studies into their viability for biomarkers, Lyme disease treatments, and rheumatoid arthritis (RA) are also being looked into. Exosomes from follicular stem cells, the logic goes, facilitate hair growth and can help prevent hair loss.
How long does it take to see results from exosome therapy for hair loss?
Exosome therapy may begin promoting natural hair growth in as little as two to three months. New hair growth can continue over the course of a year, with the most noticeable results usually being seen six months after treatment has been administered.
How long do I have to wait before another session of exosome therapy for hair loss?
We typically recommend waiting 3 to 6 months after the last treatment to re-evaluate and before potentially performing another treatment of exosome injections if it is necessary.
How are the exosomes processed, and are they safe to use?
We use exosomes which are procured and processed in the United States according to standards and regulations established by the American Association of Tissue Banks (AATB), and the United States Food & Drug Administration (FDA). All of the donors are in the United States.
Donor ethics and non-reactive FDA approved serological screening includes:
Donor consent prior to collections
HBsAG (Hepatitis B Surface Antigen)
HBcAb (Hepatitis B core Antibody)
HCV (Hepatitis C Antibody)
HIV 1/11-Ab (HIV Nucleic Acid Test)
HCV NAt (HCV Nucleic Acid Test)